Among the 80 well-categorized types, high-risk types of HPV 16 and 18 are highly involved in 70% of cervical cancer. By age 50, 80% of women will have been infected with human papillomavirus (HPV). However, infection with HPV genotypes 16 and 18 puts women at risk of developing cervical cancer, 2 If left untreated or not detected until it reaches an advanced stage, cervical cancer can be fatal. 3.Four out of five women of childbearing potential become infected with HPV at some point in their lives.
Most of these infections go away on their own, but for about five percent of women, the infection becomes chronic. Chronic HPV infection can cause precancerous lesions and cervical cancer. HPV types 16 and 18 cause about 70 percent of all cervical cancer cases and most high-grade precancerous lesions. There are also several other high-risk types of HPV that can cause precancerous lesions and cervical cancer.
Many types of HPV have no symptoms. For women who are sexually active, there is an HPV screening test that can detect the strains of HPV most commonly related to cervical cancer. During this test, a trained health professional takes a sample of cells from a woman's cervix. This sample is analyzed by a pathologist.
A pathologist is a doctor who specializes in interpreting laboratory tests and evaluating cells, tissues, and organs to diagnose diseases. The HPV test can be done alone or with a Pap smear. Pap smears look for any abnormal changes in the sample of cells removed from the cervix. Often, both tests can use the same sample.
About 12 types of HPV are considered to be at high risk for cervical cancer. Two of these types (HPV 16 and HPV 1) cause about 7 out of 10 (70%) cases of cervical cancer. In addition, in all regions of the world, the contribution of HIV to cervical cancer falls disproportionately on younger women. An abnormal cervical screening result means that you have changes in the cells that cover the cervix (cervix).
Positive HPV 16 or 18 does not mean you will develop cervical cancer, but it does mean that any dysplasia found on a Pap smear carries a higher risk of developing into cancer. While HPV can be transmitted during sexual contact, including vaginal, anal, and oral sex, sex is not the only way the infection spreads. Most men and women who have ever had sex get at least one type of genital HPV at some point in their lives. Practicing safer sex using barrier methods, such as condoms, will reduce the risk of contracting and transmitting HPV.
If they are not eligible for ablative treatment or if there is suspicion of cervical cancer, women should be referred to the appropriate level of health services, where appropriate evaluation can be performed with colposcopy and biopsies. However, there is a relatively complete paucity of data from Yemen regarding the association between HPV and cervical cancer. Even so, condoms do provide some protection against HPV and also help protect against other sexually transmitted infections. The Centers for Disease Control and Prevention (CDC) Advisory Committee on Immunization Practices (ACIP) recommends HPV vaccination to prevent new HPV infections and cancers and other HPV-associated diseases.
Because a vaccine can only prevent HPV infection, people should get vaccinated before starting sex. However, while you may not have symptoms of HPV infection, that doesn't mean you no longer have the virus in your body. Positive controls (SiHa cells infected with HPV 16 and HeLa cells infected with HPV 18 embedded in paraffin wax) and negative controls (blank paraffin wax block) were also used for quality control. The findings of this study showed prevalence rates of 48% for HPV-RA type 16 and 20.7% for HPV-RA type 18.